Introduction: Urinary tract infections (UTIs) are among the most common infectious diseases in outpatient and inpatient practice.
Aim: to analyze some epidemiological aspects of UTIs in large hospitals of the Altai Territory (AK) for 2007–2017 yy.
Materials and methods: a retrospective analysis of UTI incidence, including acute and chronic pyelonephritis, acute and chronic cystitis in the AK for 2007–2017, as well as in large medical organizations (MO) AK (KGBUZ «Altai regional hospital for war veterans» and KGBUZ. «Regional clinical hospital») was done. The main uropathogens in patients who were treated in the MO of AK were determined and the sensitivity of isolated microorganisms to antimicrobial drugs and disinfectants was analyzed.
Conclusion: a knowledge of the modern structure of uropathogens and systematic analysis of their sensitivity to antimicrobial drugs is of outmost practical importance and ensures a timely and individualized approach to the empirical antibiotic therapy even before the results of urine culture are known as well as allows to select proper disinfectants in the MO.

Keywords: disinfectant resistance, epidemiological aspects, antibiotic resistance, morbidity, urinary tract infections