Русский
Mechanisms of kidney damage
DOI: https://dx.doi.org/10.18565/urology.2019.2.103-107
A.I. Tarasenko, A.V. Alekseev, S.Yu. Maksimova
1) FGAOU VO I.M. Sechenov First Moscow State Medical University, Moscow, Russia; 2) FGBOU VO “Bashkir State Medical University” of the Ministry of Health of the Russia, Ufa, Russia
The results of recent studies on the mechanisms of kidney damage are presented in the review of literature. The role of the immune system in the occurrence, development and outcome of damage to the epithelium of the renal tubules, as well as molecular, genetic and metabolic changes which determine the extent and consequences of renal trauma are described in details. The mechanisms of restoration of the renal parenchyma and the development of fibrosis following the cessation of injury are given.
About the Autors
Corresponding author: A.V. Alekseev – Ph.D., Associate Professor at the Department of Urology with a course of IDPO of Bashkir State Medical University, Ufa, Russia; e-mail: alekseevdlt@mail.ru
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