In recent years, the quality of germinal cells has been recognized as the main factor determining reproductive potential. Standard sperm analysis is of limited value for predicting both the achievement of a pregnancy and the outcomes of assisted reproductive technologies, which raises the question of the additional significance of functional testing. Most current guidelines recommend to perform additional studies from a scientific point of view, recognizing their importance, but don’t include men in the basic diagnostic schemes. In this review, we try to discuss of the relevance of special sperm testing.

Keywords: barren marriage, ART programs, sperm analysis, male infertility, antioxidants