Bidirectionality of cardiovascular risk 
factors in patients with urolithiasis: 
current state of the problem


DOI: https://dx.doi.org/10.18565/urology.2021.4.132-137

I.T. Murkamilov, K.A. Aitbaev, V.V. Fomin, Zh.A. Murkamilova, F.A. Yusupov, A.I. Schastlivenko

1) I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan; 2) Research Institute of Molecular Biology and Medicine, Bishkek, Kyrgyzstan; 3) I.M. Sechenov First Moscow State Medical University, Moscow, Russia; 4) Kyrgyz Russian Slavic University, Bishkek, Kyrgyzstan; 5) Osh State University, Osh, Kyrgyzstan; 6) Vitebsk State Order of Peoples Friendship Medical University, Vitebsk, Belarus
The most common risk factors for cardiovascular disease and urolithiasis are presented in the article. Data on the prevalence of urolithiasis are discussed, as well as the pathogenetic mechanisms of stone formation in patients with metabolic syndrome, dyslipidemia, and arterial hypertension. The bi-directional relationship of cardiovascular risk factors and urolithiasis is generalized. The role of calcium, uric acid, citrate, changes in urine pH and an increase in body weight in the formation of kidney stones is shown.

About the Autors


Corresponding author: I.T. Murkamilov – Ph.D., acting associate professor of Department of Faculty Internal Medicine of I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan; е-mail: murkamilov.i@mail.ru


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