Новое слово в лечении больных гиперактивным мочевым пузырем. Мирабегрон: прошлое, настоящее, будущее


DOI: https://dx.doi.org/10.18565/urology.2018.5.170-174

Е. С. Коршунова

1 ФГБУ «Национальный медицинский исследовательский центр радиологии» МЗ РФ, Москва, Россия; 2 ФГБНУ «Научный центр неврологии», Москва, Россия; 3 ФГБУ ДПО «Центральная государственная медицинская академия», Москва, Россия
Симптомы гиперактивного мочевого пузыря встречаются у 16% мужчин и у 16,9% женщин.
В настоящее время первой линией терапии данного состояния считаются м-холиноблокаторы. В Российской Федерации для лечения таких пациентов доступны селективные и неселективные антимускариновые препараты. Ряд больных отказываются от долгосрочного приема м-холиноблокаторов либо в связи с побочными эффектами, либо из-за недостаточной эффективности. Это обстоятельство побудило мировое научное сообщество к поиску альтернативных методов терапии. Мирабегрон – селективный агонист β3-адренорецепторов, новое слово в лечении больных гиперактивным мочевым пузырем. В статье рассмотрены вопросы изучения адренорецепторов, свойства мирабегрона и возможности его применения.
Ключевые слова: гиперактивный мочевой пузырь, мирабегрон, агонист β3-адренорецепторов, бежевые адипоциты, хроническая сердечная недостаточность

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Об авторах / Для корреспонденции


А в т о р д л я с в я з и: Е. С. Коршунова – к.м.н., старший научный сотрудник, доцент, Москва, Россия; e_korshunova@mail.ru


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