The role of drug therapy in the management of varicocele


DOI: https://dx.doi.org/10.18565/urology.2018.5.114-121

S.I. Gamidov, V.M. Popkov, T.V. Shatylko, A.Yu. Popova, A.Yu. Korolev, R.I. Ovchinnikov, N.G. Gasanov

1V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia; 2Saratov State Medical University n. a. V. I. Razumovsky of Minzdrav of Russia, Saratov, Russia
Varicocele-related infertility is traditionally considered an indication for surgery. At the same time in some specific clinical settings, especially with subclinical varicocele, conservative therapy using hormonal or antioxidant drugs is also possible. The potential role of drug therapy in this patient category remains controversial. The article discusses the options and treatment regimens for men with varicocele-related infertility. Given the difficulties in interpreting the results of studies and the heterogeneity of the data, it is not yet possible to recommend abandoning varicocelectomy in favor of drug therapy. The most promising option for drug therapy is adjuvant antioxidants after surgical treatment of varicocele.
Keywords: varicocele, male infertility, conservative therapy, antioxidant therapy

About the Autors


Corresponding author: T. V. Shatylko – Teaching Assistant at the Department of Urology, Saratov State Medical University n. a.
V. I. Razumovsky of Minzdrav of Russia, Saratov, Russia; e-mail: shatylko@sar-urology.ru


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