Aim: to study the possibility and safety of performing simultaneous bilateral laparoscopic nephrectomy in symptomatic patients with autosomal dominant polycystic kidney disease (ADPKD) as a preparation for kidney transplantation.
Materials and methods. From May 2018 to September 2019, six symptomatic patients with end-stage renal disease caused by ADPKD, who had hemodialysis, underwent simultaneous bilateral laparoscopic nephrectomy. The mean vertical kidney size according to CT data was 211.67±37.15 mm, the mean horizontal size was 145.36±19.53 mm. In 5 cases, the hand-assisted procedure was performed.
Results. The average duration of the procedure was 225.1±40.37 minutes. Postoperative complications were recorded in 2 (33.2%) patients. The average length of stay was 8.83±2.13 days. There were no clinical manifestations of adrenal insufficiency. All patients are alive. In two patients, cadaveric kidney transplantation was performed after laparoscopic bilateral nephrectomy.
Conclusion. Laparoscopic bilateral nephrectomy in patients with chronic renal failure associated with ADPKD is feasible, safe and is associated with a short length of stay. This procedure improves the quality of life of patients and facilitates subsequent kidney transplantation.

Keywords: bilateral laparoscopic nephrectomy, polycystic disease, end-stage renal failure, autosomal dominant polycystic kidney disease (ADPKD), kidney transplantation