Lower urinary tract infections in women represent an urgent medical and social problem due to their high prevalence, frequent recurrences, and the need for an interdisciplinary approach to diagnosis and treatment. Timely and adequate diagnosis of the causes of urinary disorders in women with the determination of risk factors, concomitant diseases and isolation of pathogens allows to choose a rational therapy that may alleviate patient’s symptoms, improve the quality of life, and prevent the transformation of the disease to a chronic form. It is extermely important that treatment should not contribute to the growth of antibiotic resistance of pathogens, not disrupt the normal microbiome, and not aggravate the disturbances of the normal vaginal and intestinal microflora in women.

Keywords: urofuragin, nitrofurans, uncomplicated lower urinary tract infections, antibiotic therapy, E. coli