Русский
Sources of bacterial penetration into the kidney (review – part II)
DOI: https://dx.doi.org/10.18565/urology.2021.3.140-144
M.I. Kogan, Y.L. Naboka
1) Dept. of Urology and Human Reproductive Health (with the Pediatric Urology and Andrology Course) Rostov State Medical University, Rostov-on-Don, Russia; 2) Dept. of Microbiology and Virology №1 Rostov State Medical University, Rostov-on-Don, Russia
Kidney and upper urinary tract infections are a serious general medical problem that is the subject of ongoing experimental and clinical research. However, etiological factors and the pathophysiological mechanisms of acute infectious renal inflammation are poorly understood. This also applies to the problem of sources of bacterial penetration into the kidney. The existing hypotheses on this score have «blank spots». This review comprehensively examines the pathways of invasion of microorganisms into the kidney, causing the development of acute inflammation in it.
The proofs in favour of the existing views and their criticism are presented. Also, weaknesses in the inference system are determined.
The proofs in favour of the existing views and their criticism are presented. Also, weaknesses in the inference system are determined.
Keywords: translocation of bacteria from the intestine, the hematogenous pathway of infection, ascending pathway of infection, uropathogens invasion pathways into the kidney, bacteremia
About the Autors
Corresponding author: Mikhail I. Kogan – Honored Scientist of the Russian Federation, M.D., Dr. Sc. (M), Full Prof.; Head, Dept. of Urology and Human Reproductive Health (with the Pediatric Urology and Andrology course), Rostov State Medical University, Rostov-on-Don, Russia; e-mail: dept_kogan@mail.ru
