Русский
Modern molecular-genetic aspects of histological variants of renal cell carcinoma
DOI: https://dx.doi.org/10.18565/urology.2022.2.130-135
Y.I. Osmanov, E.A. Kogan, Z.K. Gadzhieva, D.D. Prochenko
1) Department of Pathology, I.M. Sechenov First Moscow State Medical University, Moscow, Russia; 2) Department for the Analysis of Personnel Policy, Educational Programs and Scientific Research of the National Medical Research Center on the profile «Urology» of the Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia
The article presents the main molecular mechanisms of the pathogenesis of renal cell carcinoma. The molecular pathways that determine the development of histological variants of renal cell carcinoma and the role of stem cells markers in the carcinogenesis of these tumors are considered.
Keywords: von Hippel-Lindau syndrome, Bert-Hogg-Dube syndrome, molecular diagnostics, renal cell carcinoma, stem cells
About the Autors
Corresponding author: Y.I. Osmanov - MD, professor of Department of Pathology named after A.I. Strukov of I.M. Sechenov First Moscow State Medical University, Moscow, Russia; e-mail: osmanovyouseef@yandex.ru
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