The results of a search in PubMed and Elibraru.ru databases using the keywords “autonomic regulation”, “kidney function”, “bladder function”, “ECG monitoring”, “PET/CT of the brain” are presented in the review. A regulation of bladder functions, control of blood pressure, heart rate and specialized functions of the nephron are discussed, which are in close relationship with the stem and cortical centers of the brain. The review presents an update at their cause-and-effect relationship and the place of each system in the formation of the general autonomic tone. The proposed integrative approach to the study of this problem will reveal previously unknown autonomous properties of the organs that form this physiological axis and determine the role of cortical dysfunction in the development of visceral pathology, which is fundamentally important for understanding the mechanisms of formation and recurrence of many urological diseases.

Keywords: PET/CT of the brain, ECG monitoring, bladder, kidney