The review article presents information from foreign and domestic authors on the relevance of studying the incidence of men with bening prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). Complex urodynamic studies (CUDS) remains the most informative test of the degree of expression of LUTS and bladder outlet obstruction (ВОО) caused by BPH. The difficulty in interpreting the results, the invasiveness and inaccessibility of CUDS in the routine practice of most medical institutions makes it necessary to perform relatively simpler and more accessible methods of research, which do not always objectively reflect the degree of urinary incontinence in older men. This fact causes a large number of complications and adverse outcomes of surgical treatment with the rapid development of BPH and obstructive symptoms. Taking into account the results of world research, the study of the urine proteome and urinary exosomes will improve the quality of diagnosis in patients with BPH and help in assessing the prognosis of the development of the disease.

Keywords: symptoms of the lower urinary tract, prostatic hyperplasia, infravesical obstruction, diagnosis