Русский
Treatment of patients with lower urinary tract symptoms in Moscow
DOI: https://dx.doi.org/10.18565/urology.2019.3.7-12
D.Yu. Pushkar, P.I. Rasner, D.V. Kotenko, A.N. Gerasimov, S.A. Shabalkin
1 Department of Urology of A.I. Evdokimov Moscow State University of Medicine and Dentistry (Head – corresponding member of RAS, professor D.Yu. Pushkar), Moscow, Russia; 2 Department of Medical informatics and statistics of I.M. Sechenov First Moscow State Medical University (Head – professor A.N. Gerasimov), Moscow, Russia
Introduction. In recent years, there has been a persistent tendency to a decrease in surgical treatment of patients with lower urinary symptoms (LUTS). This fact can be explained by variety drugs which have acceptable safety and high efficiency for treatment of urinary disorders. As part of our survey of men in Moscow region, the trends in prescribing the different drugs for the LUTS was studied. In addition, the duration of therapy and patient adherence were analyzed.
Materials and methods. A prospective multicenter epidemiological study “Characteristics of lower urinary tract symptoms in men in the Moscow region” was carried out using data obtained from April 1 to May 31, 2017 with anonymous survey of 525 men with mean age of 64.2±9.93 years, living in Moscow and went to the urologist with urinary disorders. All respondents answered questions from specially designed questionnaire consisted from 140 items. All medical data were analyzed, including received drugs, the duration of the therapy and subjective assessment of efficiency.
Results. A total of 419 patients from 525 (79.8%) received any kind of therapy. The most commonly used drugs were α-blockers, which consisted 65% of all prescriptions. Other drugs were administered significantly rarely. It is surprisingly, that 85.6% of respondents in Moscow region received the original α-blockers, not generic drugs. Satisfaction rate was 74.3%. Most of patients (58.3%) had received α-blockers for 1-3 years and 33.3% administered these drugs for more than 3 years. Combined drug therapy was the second most popular (25.5%). The most commonly used combination included α-blockers and inhibitors of 5α-reductase. In 90.6% cases the appointment was made by urologist.
Conclusion. Drug therapy is the most popular treatment in patients with LUTS. Our data suggest that α-blockers as monotherapy or in combination with inhibitors of 5α-reductase is the most often prescribed therapy. These results are in concordance with the main conclusions of international studies dedicated to this issue.
Materials and methods. A prospective multicenter epidemiological study “Characteristics of lower urinary tract symptoms in men in the Moscow region” was carried out using data obtained from April 1 to May 31, 2017 with anonymous survey of 525 men with mean age of 64.2±9.93 years, living in Moscow and went to the urologist with urinary disorders. All respondents answered questions from specially designed questionnaire consisted from 140 items. All medical data were analyzed, including received drugs, the duration of the therapy and subjective assessment of efficiency.
Results. A total of 419 patients from 525 (79.8%) received any kind of therapy. The most commonly used drugs were α-blockers, which consisted 65% of all prescriptions. Other drugs were administered significantly rarely. It is surprisingly, that 85.6% of respondents in Moscow region received the original α-blockers, not generic drugs. Satisfaction rate was 74.3%. Most of patients (58.3%) had received α-blockers for 1-3 years and 33.3% administered these drugs for more than 3 years. Combined drug therapy was the second most popular (25.5%). The most commonly used combination included α-blockers and inhibitors of 5α-reductase. In 90.6% cases the appointment was made by urologist.
Conclusion. Drug therapy is the most popular treatment in patients with LUTS. Our data suggest that α-blockers as monotherapy or in combination with inhibitors of 5α-reductase is the most often prescribed therapy. These results are in concordance with the main conclusions of international studies dedicated to this issue.
About the Autors
Corresponding author: P.I. Rasner – MD, professor at the Department of Urology of A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia; e-mail: dr.rasner@gmail.com
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