Method for evaluating the efficiency of treatment of urogenital tuberculosis
DOI: https://dx.doi.org/10.18565/urology.2020.4.10-13
S.Yu. Shevchenko, E.V. Kulchavenya, D.P. Kholtobin
1) TB Research Institute of Ministry of Health of Russia, Novosibirsk, Russia; 2) FGBOU VO Novosibirsk State Medical University of Ministry of Health of Russia, Novosibirsk, Russia
Introduction. Methods for evaluating the efficiency of treatment which were developed for pulmonary tuberculosis (absence of bacterial transmission and closure of cavities) are not suitable for urogenital tuberculosis.
Aim. To evaluate the use of scoring system for assessing the efficiency of treatment of urogenital tuberculosis.
Materials and methods. A pilot simple open-label prospective noncomparative cohort study was carried out, which included 15 patients with urogenital tuberculosis. All patients completed the urogenital tuberculosis score upon admission and after 1 month, along with standard clinical, laboratory and X-ray examinations. We developed this score to objectify evaluate the efficiency of antituberculosis therapy and it includes clinical and laboratory manifestations of urogenital tuberculosis.
Results. Eleven (73.3%) patients responded well to standard therapy, and 4 (26.7%) required therapy correction. Considering that the correction of therapy was carried out in a timely manner, the final result of the treatment was satisfactory. The efficiency of the proposed score has been demonstrated by clinical results.
Conclusion. Using the urogenital tuberculosis score for assessing the results of treatment of urogenital tuberculosis allows timely correction of therapy according to objective criteria.
About the Autors
Corresponding author: E.V. Kulchavenya – MD, professor, Chief Researcher at TB Research Institute of Ministry of Health of Russia; Head of the Department of Urology, professor at Department of Tuberculosis of FGBOU VO Novosibirsk State Medical University of Ministry of Health of Russia, Novosibirsk, Russia; e-mail: urotub@yandex.ru
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