Русский
Deterioration of male reproductive function: methods and algorithms of etiopathogenetic and empirical treatment of the main clinical forms
DOI: https://dx.doi.org/10.18565/urology.2024.5.122-131
Bozhedomov V.A., Korneev I.A., Kamalov A.A.
1) “Men's Health” Clinic, University Clinic of Lomonosov Moscow State University and Department of Urology and Andrology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow, Russia; 2) National Medical Research Center for Obstetrics, Gynecology and Perinatology named after V.I. Kulakov, Ministry of Health of the Russian Federation, Moscow, Russia; 3) LLC Men's Health Clinic "MedCode", Moscow, Russia; 4) Department of Urology of Pavlov First Saint Petersburg State Medical University of the Ministry of Health of Russia, Saint Petersburg, Russia; 5) LLC International Center of Reproductive medicine, Saint Petersburg, Russia
In half of the cases, a decrease in the quantity and/or quality of spermatozoa is the cause of infertility. The pathogenesis of such disorders is multifactorial, often unknown, and data on the treatment efficiency are still contradictory. Based on the recent high-level evidences (randomized studies and meta-analyses), the real clinical efficiency of various surgical and conservative treatment methods for the main clinical forms of male reproductive dysfunction, including hypo- and hypergonadotropic hypogonadism, secretory and obstructive azoospermia, retrograde ejaculation and anejaculation, pathospermia associated with varicocele, and idiopathic forms, is analyzed. An algorithm for managing patients with these disorders is proposed, which can be convenient in the routine practice of a urologists regardless of the level of equipment of a healthcare facility.
Keywords: azoospermia, retrograde ejaculation, anejaculation, pathospermia, oligoasthenoteratozoospermia, spermatozoa, hypogonadism, male infertility, varicocele
About the Autors
Corresponding author: Bojedomov V.A. – Ph.D., MD, professor, Head of the “Men's Health” Clinic, University Clinic of Lomonosov Moscow State University, professor at the Department of Urology and Andrology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, leading researcher at the National Medical Research Center for Obstetrics, Gynecology and Perinatology named after V.I. Kulakov, Ministry of Health of the Russian Federation, Scientific Chief of LLC Men's Health Clinic "MedCode", Moscow, Russia; e-mail: vbojedomov@mail.ru
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