A role of varicocele in the development of male infertility and methods of surgical treatment


DOI: https://dx.doi.org/10.18565/urology.2020.4.111-118

N.D. Akhvlediani, I.A. Reva, A.S. Chernushenko, A.N. Bernikov, D.Yu. Pushkar

1) Department of Urology of A.I. Evdokimov Moscow State University of Medicine and Dentistry (Head – academician of RAS, professor D.Yu. Pushkar), Moscow, Russia; 2) University Clinic “Kuskovo” of A.I. Evdokimov Moscow State University of Medicine and Dentistry (Head – academician of RAS, professor V.V. Krylov), Moscow, Russia
Varicocele is the most common and treatable cause of male infertility. Therefore, surgical treatment of varicocele should be recommended for motivated patients and infertile couples who do not have other identified causes of infertility. Varicocelectomy has been proved to improve sperm parameters and improve chances of successful conception in most patients. However, surgical treatment is associated with certain risks, and therefore, the choice of the optimal treatment is under discussion.
A total of 78 articles using a search in MEDLINE database (PubMed) were found and included in the review, dedicated to current concepts of functional anatomy of testicular arteries and veins. The current recommendations of professional communities regarding the selection of patients for varicocelectomy are described. The efficiency and safety of various surgical procedures for varicocele is analyzed. This review suggests high inconsistences in the literature. The available information on the indications for surgical treatment, as well as comparative data on the efficiency and safety of the inguinal, laparoscopic and microsurgical sub-inguinal approaches are presented. When urologist faces with a diagnosis of varicocele, individual approach should be applied, with a discussion of both benefits and possible complications of surgical treatment. Of the many existing techniques, microsurgical ligation of dilated veins is the most preferred.

About the Autors


Corresponding author: N.D. Akhvlediani – MD, professor at the Department of Urology of A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia; e-mail: nikandro@mail.ru


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