The review is devoted to assessing the state of the problem of infectious and inflammatory diseases of the bladder of viral etiology, their pathogenesis, differential diagnosis, and treatment features. The search was conducted using Medline, PubMed, and EMBASE databases. Data from a literature search indicate that the problem of chronic recurrent cystitis (CRC) of viral etiology is widely represented in the press and in search databases. Such attention is due to the difficulties of diagnostics, differential diagnostics, lack of treatment standards, and the recurrent course of the process. In most cases, with a clinical picture of recurrent urinary tract infection, even in the absence of leukocyturia and bacteriuria, antibacterial therapy (AB) is prescribed, which not only does not lead to an improvement in the condition if there is a viral infection of the bladder, but in some cases only worsens the clinical symptoms.
Objective: to identify the characteristics of the course of chronic recurrent cystitis of viral etiology, to determine differential diagnostic criteria for the development of the infectious process caused by various viral agents, taking into account their pathogenic properties.

Keywords: viral cystitis, chronic recurrent cystitis, urothelium, human papillomavirus