Тестостерон-заместительная терапия при мужском гипогонадизме: взгляд из 21 века


DOI: https://dx.doi.org/10.18565/urology.2025.1.93-103

Раснер П.И., Рева И.А., Карамышева Е.И., Алиев Р.И.

Научно-образовательный институт клинической медицины им. Н.А. Семашко ФГБОУ ВО «Российский университет медицины» (директор – д.м.н., профессор А.А. Солодов), Москва, Россия
Распространенность симптоматического постпубертатного гипогонадизма у мужчин 40–79 лет составляет 2,1–5,7% и увеличивается с возрастом. Тестостерон-заместительная терапия призвана восстановить уровень тестостерона в плазме крови до нормальных среднефизиологических значений и обеспечивает многочисленные положительные клинические эффекты: улучшение сексуальной функции, снижение выраженности симптомов депрессии, улучшение настроения, нормализацию мышечно-жирового соотношения состава тела и минеральной плотности костей и многие другие. Рекомендации, приведенные в различных руководствах по терапии тестостероном, не позволяли составить однозначное мнение о безопасности длительной тестостерон-заместительной терапии.
Настоящая работа посвящена анализу эффективности тестостерон-заместительной терапии в лечении основных симптомов постпубертатного гипогонадизма, ее влиянию на сопутствующие соматические заболевания, безопасности и разумному выбору лекарственной формы препарата тестостерона.

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Об авторах / Для корреспонденции


А в т о р д л я с в я з и: П. И. Раснер – д.м.н., профессор, главный врач Научно-образовательного института клинической медицины им. Н.А. Семашко ФГБОУ ВО «Российский университет медицины», Москва, Россия; e-mail: dr.rasner@gmail.com


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