Disorders of lipid metabolism as a risk factor for male infertility


DOI: https://dx.doi.org/10.18565/urology.2022.1.109-112

N.A. Kurashova, B.G. Dashiev, L.V. Rychkova, L.I. Kolesnikova

Federal State Public Scientific Institution « Scientific Centre for Family Health and Human Reproduction Problems», Irkutsk, Russia
The presented literature review analyzes and summarizes data on studies by domestic and foreign authors on one of the most pressing problems of modern andrology - the pathogenetic relationship of excess body weight and male infertility. Modern clinical, epidemiological and experimental data indicate a negative effect of obesity on the reproductive function of men. According to the WHO, in Russia 54% of men are overweight, 15% of whom are obese. The problem of obesity is independent of age, area of residence, as well as the social and professional level of men. Obesity is a predisposing factor in the development of concomitant somatic pathological processes. Oxidative stress of sperm, androgen deficiency, neuropathy is far from an exhaustive list of the most important mechanisms for the realization of the neuroendocrine and reproductive effects of overweight and obesity. The increasing number of infertile couples annually dictates the need for a reliable monitoring system to get a correct picture of the development of the obesity epidemic, as well as to quickly assess what preventive measures should be taken.

About the Autors


Corresponding author: N.A. Kurashova – Doctor of science in Biology, leading researcher of the Laboratory of Pathophysiology of Reproduction of Federal State Public Scientific Institution «Scientific Centre for Family Health and Human Reproduction Problems», Irkutsk, Russia; e-mail: nakurashova@yandex.ru


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