English
Современное представление о микробиоме мочевыделительной системы у детей
DOI: https://dx.doi.org/10.18565/urology.2025.1.141-147
Туров Ф.О., Яцык С.П., Крапивкин А.И., Врублевский С.Г., Мамедов И.С., Перевезенцев О.А.
1) ГБУЗ «Научно-практический центр специализированной медицинской помощи детям им. В.Ф. Войно-Ясенецкого ДЗ г. Москвы», Москва, Россия; 2) ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва, Россия; 3) ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, Москва, Россия
Цель исследования: провести анализ отечественных и зарубежных публикаций, посвященных изучению микробиома мочевыделительной системы у детей.
Методы культивирования или посева продолжают считаться «золотым стандартом» во многих странах для диагностики бактериальных инфекций, хотя доступны более чувствительные и специфичные технологии. Образец мочи ранее считался стерильным, если уропатогены не давали рост при использовании стандартных процедур культивирования. Остается неясным, являются ли стандартные методы культивирования микроорганизмов адекватными для определения видового разнообразия и выявления всех микроорганизмов, способных провоцировать ИМП.
Изучение здорового микробиома мочевого пузыря и поддержание его гомеостаза с целью профилактики воспалительных заболеваний нижних мочевыводящих путей является новой областью исследований. Известно, что в мочевом пузыре здорового человека содержится неуропатогенные бактерии, такие как Lactobacillus, которые, как считается, выполняют функцию иммунной системы и защищают от воздействия уропатогенных бактерий.
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Об авторах / Для корреспонденции
А в т о р д л я с в я з и: Ф. О. Туров – к.м.н., ведущий научный сотрудник, детский уролог-андролог ГБУЗ «НПЦ спец. мед. помощи детям» ДЗМ, Москва, Россия; e-mail: Filipp_100@Mail.ru
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