Преждевременная эякуляция: основные физиологические механизмы и новые подходы к лечению


DOI: https://dx.doi.org/10.18565/urology.2020.6.95-102

А.А. Камалов, Д.А. Охоботов, М.В. Фролова, А.С. Тивтикян, О.Ю. Нестерова

1) Медицинский научно-образовательный центр МГУ им. М. В. Ломоносова (дир. – академик РАН, д.м.н. А. А. Камалов), Москва, Россия; 2) факультет фундаментальной медицины, кафедра урологии и андрологии (зав. каф. – академик РАН, д.м.н. А. А. Камалов) МГУ им. М. В. Ломоносова, Москва, Россия; 3) факультет фундаментальной медицины (декан – академик РАН, д.б.н. В.А. Ткачук) МГУ им. М. В. Ломоносова, Москва, Россия
Преждевременная эякуляция (ПЭ) характеризуется ранним семяизвержением, происходящим в течение 1 мин после влагалищного проникновения или до него. Данное состояние считается самой распространенной проблемой интимного характера у мужчин, которая становится причиной развития ряда негативных психологических последствий. Для понимания этиопатогенеза заболевания необходимо иметь представление о физиологических механизмах эякуляторного рефлекса, ключевым посредником которого является группа галанинэргических поясничных спиноталамических клеток (LSt cells) с их многочисленными проекционными связями с различными структурами центральной нервной системы. Основные подходы к лечению ПЭ основаны на замедлении проведения импульса по афферентам от чувствительных рецепторов головки полового члена. В последние годы основная доля исследований по проблеме ПЭ посвящена оценке различных технологий рефлексотерапии и возможностям применения метода биологической обратной связи. Мы проанализировали имеющиеся данные литературы, подробно охарактеризовав основные звенья эякуляторного рефлекса, а также возможные подходы к терапии.

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Об авторах / Для корреспонденции


А в т о р д л я с в я з и: Д. А. Охоботов − к.м.н., врач-уролог, Медицинский научно-образовательный центр МГУ
им. М. В. Ломоносова; ст. преподаватель, кафедра урологии и андрологии, факультет фундаментальной медицины,
МГУ им. М. В. Ломоносова, Москва, Россия, e-mail: 14072003@rambler.ru


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